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Itch, or pruritus, is a common sensation that causes a person to want to scratch. It can be a major quality of life issue. Itch is a complex process that can be prompted by a variety of health impairments. It is commonly associated with skin disorders such as atopic dermatitis and urticaria or being a symptom of an underlying disease such as cholestasis or hyperthyroidism. It can also manifest from dry skin, especially in cold weather.