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Two women, one apartment, and nine very eventful months. Baby Mama is a predictable comedy about a successful and single businesswoman whose plans of having a child are thrown when she discovers she has only a million-to-one chance of getting pregnant. The film’s opening sequence shows the career-driven Kate Holbrook (Tina Fey) on a blind date, where she explains, “ Some women got pregnant, I got promoted. I want a baby now, I'm 37." Needless to say, her blind date rapidly flees the scene.

When lazy process server Dale Denton (Seth Rogen) witnesses a drug-related murder between a crooked cop and a dangerous drug lord, he and his drug dealer Saul (James Franco) have to go on the run. Dale panicked at the crime scene and dumped his joint of a rare new weed called Pineapple express, which was then traced back to Saul. The two fugitives quickly flee with the cop and his accomplice hot on their trail.